Now showing items 1-11 of 11

    • Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health 

      Maksimović-Ivanić, Danijela D.; Mijatović, Sanja A.; Tafuri, Agostino; Milella, Michele; Laidler, Piotr; Cervello, Melchiorre; Montalto, Giuseppe; Libra, Massimo; Nicoletti, Ferdinando; Mazzarino, Maria C; Malaponte, Graziella; Fagone, Paolo; Donia, Marco; Stivala, Franca; Baesecke, Joerg; Franklin, Richard A; Abrams, Stephen L; Kempf, Ruth C; Long, Jacquelyn M; Steelman, Linda S; Chappell, William H; McCubrey, James A; Martelli, Alberto M; Cocco, Lucio; Evangelisti, Camilla; Bonati, Antonio
    • Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging 

      Maksimović-Ivanić, Danijela D.; Mijatović, Sanja A.; Cervello, Melchiorre; Montalto, Giuseppe; Martelli, Alberto M; Evangelisti, Camilla; Cocco, Lucio; Baesecke, Joerg; Bonati, Antonio; Tafuri, Agostino; Milella, Michele; Libra, Massimo; Nicoletti, Ferdinando; Malaponte, Graziella; Fagone, Paolo; Donia, Marco; Mazzarino, Maria C; Stivala, Franca; Laidler, Piotr; Long, Jacquelyn M; Kempf, C Ruth; Abrams, Stephen L; Chappell, William H; Steelman, Linda S; McCubrey, James A
    • Therapeutic Resistance Resulting From Mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Signaling Pathways 

      Mijatović, Sanja A.; Maksimović-Ivanić, Danijela D.; Cocco, Lucio; Cervello, Melchiorre; Montalto, Giuseppe; Baesecke, Joerg; Libra, Massimo; Nicoletti, Ferdinando; Malaponte, Graziella; Stivala, Franca; Abrams, Stephen L; Chappell, William H; Kempf, C Ruth; Steelman, Linda S; McCubrey, James A; Martelli, Alberto M
    • Novel approaches to target the prostate cancer stem cell - eliminating the root of the cancer 

      Maksimović-Ivanić, Danijela D.; Mijatović, Sanja A.; Cervello, Melchiorre; Libra, Mussimo; Mulaponte, Graziella; Mazzarino, Clorinda; Fagone, Paolo; Nicoletti, Ferdinando; Stivala, Franca; Martelli, Alberto M; Abrams, Stephen L; Chappell, William H; McCubrey, James A; Steelman, Linda S
    • Sensitization of cancer stem cells based on inhibiting key signal transduction pathways 

      Mijatović, Sanja A.; Maksimović-Ivanić, Danijela D.; Cervello, Melchiorre; Stivala, Franca; Libra, Massimo; Malaponte, Graziella; Mazzarino, Clorinda; Fagone, Paolo; Nicoletti, Ferdinando; Martelli, Alberto M; Chappell, William H; Abrams, Stephen L; Steelman, Linda S; McCubrey, James A
    • Advances in Targeting Signal Transduction Pathways 

      Mijatović, Sanja A.; Maksimović-Ivanić, Danijela D.; Cervello, Melchiorre; Montalto, Giuseppe; Umezawa, Kazuo; Drobot, Lyudmyla; D'Assoro, Antonio B; Laidler, Piotr; Dulinska-Litewka, Joanna; Tafuri, Agostino; Milella, Michele; Baesecke, Joerg; Polesel, Jerry; Nicoletti, Ferdinando; Donia, Marco; Fagone, Paolo; Mazzarino, Maria C; Malaponte, Graziella; Ligresti, Giovanni; Candido, Saverio; Libra, Massimo; Martelli, Alberto M; Chiarini, Francesca; Evangelisti, Camilla; Cocco, Lucio; Franklin, Richard A; Abrams, Stephen L; Davis, Nicole M; Sun, Lin; Chappell, William H; Steelman, Linda S; McCubrey, James A; Talamini, Renato; Demidenko, Zoya N
    • Mutations and Deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascades Which Alter Therapy Response. 

      Mijatović, Sanja A.; Maksimović-Ivanić, Danijela D.; Evangelisti, Camilla; Cocco, Lucio; Tafuri, Agostino; Milella, Michele; Baesecke, Joerg; Libra, Massimo; Candido, Saverio; Mazzarino, Maria C; Martelli, Alberto M; Fagone, Paolo; Nicoletti, Ferdinando; Cervello, Melchiorre; Montalto, Giuseppe; Abrams, Stephen L; Chappell, William H; Steelman, Linda S; McCubrey, James A; Malaponte, Graziella; Chiarini, Francesca
    • Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascade Inhibitors: How Mutations Can Result in Therapy Resistance and How to Overcome Resistance 

      Maksimović-Ivanić, Danijela D.; Mijatović, Sanja A.; Chiarini, Francesca; Tafuri, Agostino; Milella, Michele; Baesecke, Joerg; Nicoletti, Ferdinando; Fagone, Paolo; Mazzarino, Maria C; Malaponte, Graziella; Chappell, William H; Steelman, Linda S; McCubrey, James A; Libra, Massimo; Candido, Saverio; Cervello, Melchiorre; Montalto, Giuseppe; Franklin, Richard A; Abrams, Stephen L; Cocco, Lucio; Martelli, Alberto M; Evangelisti, Camilla
    • Targeting the Cancer Initiating Cell: The Ultimate Target for Cancer Therapy 

      Mijatović, Sanja A.; Maksimović-Ivanić, Danijela D.; Cocco, Lucio; Evangelisti, Camilla; Bonati, Antonio; Laidler, Piotr; Cervello, Melchiorre; Montalto, Giuseppe; Stivala, Franca; Ligresti, Giovanni; Libra, Massimo; Nicoletti, Ferdinando; Baesecke, Joerg; Chappell, William H; Misaghian, Negin; Abrams, Stephen L; Steelman, Linda S; McCubrey, James A; Martelli, Alberto M
    • Targeting signaling pathways in prostate cancer 

      Mijatović, Sanja A.; Maksimović-Ivanić, Danijela D.; Libra, Massimo; Malaponte, Graziella; Mazzarino, Clorinda; Fagone, Paolo; Nicoletti, Ferdinando; Martelli, Alberto M; Abrams, Stephen L; Chappell, William H; Steelman, Linda S; Montalto, Giuseppe; Umezawa, Kazuo; McCubrey, James A; Cervello, Melchiorre
    • Role of NGAL (Lcn2) in prostate cancer invasion 

      Mijatović, Sanja A.; Maksimović-Ivanić, Danijela D.; Maestro, Roberta; Talamini, Renato; Polesel, Jerry; Cervello, Melchiorre; Libra, Massimo; Fagone, Paolo; Nicoletti, Ferdinando; Martelli, Alberto M; Abrams, Stephen L; Chappell, William H; McCubrey, James A; Steelman, Linda S