РАДаР - Репозиторијум Архивираних Дигиталних Радова
Институт за биолошка истраживања "Синиша Станковић"
    • English
    • Српски
    • Српски (Serbia)
  • Српски (ћирилица) 
    • Енглески
    • Српски (ћирилица)
    • Српски (латиница)
  • Пријава
Преглед рада 
  •   ИБИСС РАДаР
  • IBISS
  • Article
  • Преглед рада
  •   ИБИСС РАДаР
  • IBISS
  • Article
  • Преглед рада
JavaScript is disabled for your browser. Some features of this site may not work without it.

Advances in Targeting Signal Transduction Pathways

2012
Аутори:
McCubrey, James A
Steelman, Linda S
Chappell, William H
Sun, Lin
Davis, Nicole M
Abrams, Stephen L
Franklin, Richard A
Cocco, Lucio
Evangelisti, Camilla
Chiarini, Francesca
Martelli, Alberto M
Libra, Massimo
Candido, Saverio
Ligresti, Giovanni
Malaponte, Graziella
Mazzarino, Maria C
Fagone, Paolo
Donia, Marco
Nicoletti, Ferdinando
Polesel, Jerry
Talamini, Renato
Baesecke, Joerg
Mijatović, Sanja A.
Maksimović-Ivanić, Danijela D.
Milella, Michele
Tafuri, Agostino
Dulinska-Litewka, Joanna
Laidler, Piotr
D'Assoro, Antonio B
Drobot, Lyudmyla
Umezawa, Kazuo
Montalto, Giuseppe
Cervello, Melchiorre
Demidenko, Zoya N
Тип документа:
Приказ
Метаподаци
Приказ свих података о документу
Апстракт:
Over the past few years, significant advances have occurred in both our understanding of the complexity of signal transduction pathways as well as the isolation of specific inhibitors which target key components in those pathways. Furthermore critical information is being accrued regarding how genetic mutations can affect the sensitivity of various types of patients to targeted therapy. Finally, genetic mechanisms responsible for the development of resistance after targeted therapy are being discovered which may allow the creation of alternative therapies to overcome resistance. This review will discuss some of the highlights over the past few years on the roles of key signaling pathways in various diseases, the targeting of signal transduction pathways and the genetic mechanisms governing sensitivity and resistance to targeted therapies.
Извор:
Oncotarget, 2012, 3, 12, 69-1521

ISSN: 1949-2553

[ Google Scholar ]
URI
http://ibiss-r.rcub.bg.ac.rs/123456789/1071
Колекције
  • Article
Институција
IBISS

DSpace software copyright © 2002-2015  DuraSpace
О ИБИСС РАДаР репозиторијуму | Пошаљите запажања

OpenAIRERCUB
 

 

Комплетан репозиторијумКолекцијеАуториПо датуму издавањаТемеОва институцијаАуториПо датуму издавањаТеме

DSpace software copyright © 2002-2015  DuraSpace
О ИБИСС РАДаР репозиторијуму | Пошаљите запажања

OpenAIRERCUB