Wavelet and fractal analysis of rat brain activity in seizures evoked by camphor essential oil and 1,8-cineole
Grbić, Gordana M.
Sekulić, Slobodan R
Чланак у часопису
МетаподациПриказ свих података о документу
We investigated the rat brain activity in acute seizures evoked by camphor essential oil or its main constituent 1,8-cineole by wavelet (primarily) and fractal analysis. Experiments were performed on anesthetized animals before and after intraperitoneal camphor oil or cineole administration. The properties of frequency bands in pre-ictal, ictal and inter-ictal stages have been determined by wavelet analysis. The domination of 6 frequency band was confirmed in obtained brain activities, which participate with approximate to 45% of mean relative wavelet energy (MRWE) in control signals and arise up to approximate to 76% MRWE in energy spectrum during the ictal stage (after drug administration). Other frequency bands decreased during ictal stage and arised in inter-ictal stage. There was a dose-dependent response of cineole effect: increase in cineole concentration leaded to the higher values of relative wavelet energy (RWE) of delta frequency band while there were slight changes of the mean fractal dimension (FD) values as a measure of system complexity.
Извор:General Physiology and Biophysics, 2009, 28, null, 289-40