The effects of exposure to extremely low-frequency magnetic field and amphetamine on the reduced glutathione in the brain
Аутори:Jelenković, Ankica V.
Janac, Branka B.
Pesić, Vesna T
Jovanović, Marina D
Vasiljević, Ivana D
Prolić, Zlatko M.
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Continuous exposure to extremely low-frequency magnetic field (ELF-MF, 50 Hz, 0.5 mT) alone and combined with D-amphetamine (1.5 mg/kg) affected the reduced glutathione content in brain regions of rats. Compared to sham-exposed rats, the glutathione content in the forebrain cortex of the ELFMF-exposed rats decreased (P < 0.001), but this reverted after giving amphetamine upon ELF-MF exposure. In this group, the glutathione content was increased in the brain stem and cerebellum (P < 0.05 compared to the shame-exposed, ELM-MF-exposed, and amphetamine-treated groups). It is suggested that biogenic monoamines are involved in the reduced glutathione changes observed. The changes are not uniform in the brain regions examined.