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dc.creatorRashed, Khaled
dc.creatorĆirić, Ana D.
dc.creatorGlamočlija, Jasmina
dc.creatorSoković, Marina D.
dc.date.accessioned2016-05-23T11:00:29Z
dc.date.issued2014
dc.identifier.issn1872-633X
dc.identifier.urihttp://ibiss-r.rcub.bg.ac.rs/123456789/2185
dc.description.abstractThis study was carried out with the objective to investigate antibacterial and antifungal activities of Diospyros virginiana fruits (methanol 80\%) extract and the phenolic compounds isolated from the extract. The in vitro antibacterial and antifungal assays were done against eight bacterial strains and against eight fungal species using microdilution method. Eight phenolic compounds, m-gallate, gallic acid, luteolin, quercetin, myricetin, myricetin 3-O-alpha-rhamnoside, myricetin 3-O-beta-glucoside, and myricetin 3-O-beta-glucuronide were isolated and identified by different spectroscopic tools (UV, H-1 NMR, C-13 NMR, MS). The results of the methanol extract of Diospyros virginiana fruits and its isolated phenolic compounds showed significant antibacterial and antifungal effects against all the tested microorganisms. The best results were obtained for flavonoid aglycones which showed strong antimicrobial activity against all the microorganisms tested. These results may help to discover new chemical classes of natural antimicrobial substances that could serve as selective agents for infectious disease chemotherapy and control. (C) 2014 Published by Elsevier B.V.
dc.description.sponsorshipSerbian Ministry of Education, Science and Technological Development {[}173032]
dc.languageEnglish
dc.sourceIndustrial Crops and Products
dc.subjectDiospyros virginiana
dc.subjectFruits
dc.subjectPhenolic compounds
dc.subjectAntibacterial
dc.subjectAntifungal
dc.titleAntibacterial and antifungal activities of methanol extract and phenolic compounds from Diospyros virginiana L.
dc.typearticle
dcterms.abstractЋирић, Aна Д.; Расхед, Кхалед; Гламочлија, Јасмина; Соковић, Марина Д.;
dc.citation.volume59
dc.identifier.doi10.1016/j.indcrop.2014.05.021
dc.identifier.wos000339600400031
dc.citation.spage210
dc.citation.epage215


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