Antioxidant and antimicrobial activities of a purified polysaccharide from yerba mate (Ilex paraguariensis)
Authors:Kungel, Pâmela T.A.N.
Correa, Vanesa G.
Corrêa, Rúbia C.G.
Peralta, Rosely Aparecida
Calhelha, Ricardo C.
Ferreira, Isabel C.F.R.
Peralta, Rosane M.
© 2018 Elsevier B.V.
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This study investigated the antioxidant, antimicrobial and cytotoxic properties of a purified yerba mate polysaccharide. The yerba mate polysaccharide showed a prominent antioxidant activity as evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH)-radical scavenging activity (IC50=1.25±0.10mg/mL), 3-ethyl benzothiazoline-6-sulphonic acid (ABTS+)-radical scavenging activity (IC50=0.41±0.05mg/mL), and hydroxyl scavenging activity (IC50=3.36±0.31mg/mL). The antioxidant activity evaluated as the ferric ion reduction power (FRAP) and oxygen radical absorbance radical assay (ORAC), expressed as trolox equivalents, were 20.84±1.61μMTE/mg and 556.30±12.83μMTE/mg, respectively. The purified yerba mate polysaccharide presented high antimicrobial activity against several bacterial and fungal strains; however, no cytotoxicity against all four tumor human cell lines assessed.
Keywords:Antioxidant activity; Antimicrobial activity; Polysaccharide; Yerba mate
Source:International Journal of Biological Macromolecules, 2018, 114, 1161-1167
- Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq, Proc. 3079/2015-8)
- Coordenação de Aperfeiçoamento do Pessoal do Ensino Superior (CAPES)
- CAPES Foundation, Ministry of Education, Brazil (process number 88881.120010/2016–01)