Antifungalna i antioksidativna aktivnost etarskog ulja Mentha longifolia (L.) Huds. (Lamiaceae)
Antifungal and antioxidant activity of Mentha longifolia (L.) Hudson (Lamiaceae) essential oil
Authors:Džamić, Ana M.
Ristić, Mihailo S.
Grujić-Jovanović, Slavica M.
Marin, Petar D.
Article (Published version)
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The present study describes the antifungal and antioxidant activity of Mentha longifolia (L.) Hudson essential oil. This plant is native to Europe, Central Asia and Australia. It is used as carminative, stomachic and stimulant and also in aromatherapy. The essential oil profile was determined by GC and GC-MS. The main compounds in the oil were trans-dihydrocarvone (23.64%), piperitone (17.33%) and cis-dihydrocarvone (15.68%). Minimum inhibitory concentrations (MIC) and minimum fungicidal concentrations (MFC) were recorded using the microdilution method. Commercial antimicotic bifonazol was used as a control. The concentration of 10 μl/ml showed fungicidal activity against Aspergillus and Fusarium species, Penicillium funiculosum and Trichoderma viride. Concentration of 5 μl/ml was efficient against Trichophyton menthagrophytes and yeast Candida albicans. The most sensitive micromycetes were Cladosporium fulvum, C. cladosporium cladosporioides and Penicillium ochrochloron where concentration of 2.5 μl/ml was lethal. The antioxidant activity of essential oil was evaluated by means of the 2,2-diphenyl-1-picrylhydrazil (DPPH) radical scavenging method. The essential oil of M. longifolia was able to reduce DPPH radicals into the DPPH-H form, and this activity was dose-dependent. The oil exhibited significant potential for antioxidant activity, and reduced DPPH to 50% (IC50=0,659 ml/ml of solution). .