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dc.creatorPopov, Aleksandra D.
dc.creatorMirkov, Ivana
dc.creatorKataranovski, Milena
dc.date.accessioned2017-11-23T11:05:49Z
dc.date.available2015-11-17T10:26:51Z
dc.date.issued2012sr
dc.identifier.issn0257-277Xsr
dc.identifier.otherRad_konverzija_3188sr
dc.identifier.urihttps://ibiss-r.rcub.bg.ac.rs/handle/123456789/1193
dc.description.abstractContact hypersensitivity (CHS) is a T-cell-mediated skin inflammatory reaction to cutaneous exposure to small sensitizing chemicals, haptens. Majority of CHS studies were conducted in mice and there is paucity of data in other experimental animals. In this review, after a brief survey of murine CHS, hitherto known characteristics of CHS in rats were presented including inflammatory and immune mechanisms of both sensitization and elicitation phases. Survey of literature of rat CHS is presented, with our data concerning the importance of genetic background both in the induction and in the expression of reaction to dinitrochlorobenzene. The knowledge of CHS in rats, preferred animal in immunopharmacological studies, might help development of immunomodulatory intervention in contact allergy.en
dc.description.sponsorshipMinistry of Education and Science of the Republic of Serbia [173039]sr
dc.language.isoEnglishsr
dc.rightsrestrictedAccess
dc.sourceImmunologic Researchsr
dc.titleInflammatory and immune mechanisms in contact hypersensitivity (CHS) in ratsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractПопов, Aлександра Д.; Мирков, Ивана; Катарановски, Милена В.;
dc.citation.issue1-2sr
dc.citation.volume52sr
dc.citation.epage132sr
dc.type.versionpublishedVersionen
dc.citation.rankM22


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