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dc.creatorPetrović, Jovana
dc.creatorGlamočlija, Jasmina
dc.creatorStojković, Dejan
dc.creatorNikolić, Miloš
dc.creatorĆirić, Ana
dc.creatorFernandes, Angela
dc.creatorFerreira, Isabel C. F. R.
dc.creatorSoković, Marina
dc.date.accessioned2016-05-23T11:00:42Z
dc.date.available2016-05-23T11:00:42Z
dc.date.issued2014
dc.identifier.issn2042-650X
dc.identifier.urihttps://ibiss-r.rcub.bg.ac.rs/handle/123456789/2267
dc.description.abstractAgrocybe aegerita (Brig.) Sing is a basidiomycete, white rot fungus. Antimicrobial activities and the antiqourum effect on Pseudomonas aeruginosa of an A. aegerita methanolic extract were investigated. The extract showed very good antimicrobial activity against all the tested microorganisms in a dose dependent manner. Effects of the Sub-MIC, MIC and 2MIC of the A. aegerita methanolic extract regulated the virulence factors in the quorum sensing (QS) test, as well as biofilm formation on P. aeruginosa. Sub-inhibitory and inhibitory concentrations of the extract demonstrated the reduction of virulence factors such as pyocyanin production, twitching and swimming motility. The biofilm forming capability of P. aeruginosa PAO1 was also reduced in a concentration-dependent manner. Furthermore, the chemical composition of the methanolic extract was determined considering its phenolic composition. The methanolic extract of A. aegerita can be a very good source of bioactive substances. This research is of great importance due to the prevalence of drug-resistant microorganisms.
dc.description.sponsorshipMinistry of Education, Science and Technological Development of Serbia {[}173032]; Foundation for Science and Technology (FCT, Portugal) {[}SFRH/BD/76019/2011]
dc.languageEnglish
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173032/RS//
dc.relationFoundation for Science and Technology (SFRH/BD/76019/2011)
dc.rightsrestrictedAccess
dc.sourceFood & Function
dc.titleBioactive composition, antimicrobial activities and the influence of Agrocybe aegerita (Brig.) Sing on certain quorum-sensing-regulated functions and biofilm formation by Pseudomonas aeruginosa
dc.typearticle
dc.rights.licenseARR
dcterms.abstractФернандес, Aнгела; Ферреира, Исабел Ц. Ф. Р.; Петровиц, Јована; Стојковиц, Дејан; Гламочлија, Јасмина; Николиц, Милос; Ћирић, Aна Д.; Соковић, Марина Д.;
dc.rights.holder© 2014 Royal Society of Chemistry
dc.citation.issue12
dc.citation.volume5
dc.identifier.doi10.1039/c4fo00819g
dc.identifier.scopus2-s2.0-84912063407
dc.identifier.wos000345454700027
dc.citation.spage3296
dc.citation.epage3303
dc.type.versionpublishedVersionen


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