Show simple item record

dc.creatorKračun-Kolarević, Margareta
dc.creatorKolarević, Stoimir
dc.creatorJovanović, Jovana
dc.creatorMarković, Vanja
dc.creatorIlić, Marija
dc.creatorSimonović, Predrag
dc.creatorSimić, Vladica
dc.creatorGačić, Zoran
dc.creatorDiamantini, Elena
dc.creatorStella, Elisa
dc.creatorPetrović, Mira
dc.creatorMajone, Bruno
dc.creatorBellin, Alberto
dc.creatorPaunović, Momir
dc.creatorVuković-Gačić, Branka
dc.date.accessioned2017-01-17T12:45:37Z
dc.date.available2017-01-17T12:45:37Z
dc.date.issued2016
dc.identifier.issn0048-9697
dc.identifier.urihttp://linkinghub.elsevier.com/retrieve/pii/S0048969716315455
dc.identifier.urihttps://ibiss-r.rcub.bg.ac.rs/handle/123456789/2505
dc.description.abstractIn this study a comprehensive genotoxicological survey throughout the upper and middle stretches of Adige river basin is presented. The study was carried out at 7 sites located along the Adige main course and one the most significant tributaries, the Noce creek, both presenting different levels of pollution pressure. To give an insight into the nature of the genotoxic activity we employed the battery of prokaryotic and eukaryotic assays. Mutagenicity in water samples was evaluated by SOS/umuC test in Salmonella typhimurium TA1535/pSK1002. The level of DNA damage as a biomarker of exposure (comet assay) and biomarker of effect (micronucleus assay) and the level of oxidative stress as well (Fpg - modified comet assay) were studied in blood cells of Salmo cenerinus Nardo, 1847 and Salmo marmoratus Cuvier, 1829. Within the applied bioassays, comet assay showed the highest potential for discriminating the sampling sites which are under lesser extent of pressure (sampling sites 1-Barnes at Bresimo and 4-Noce downstream S. Giustina) from the sites under high pressure (sampling sites 5-Noce at Mezzolombardo and 6/7-Adige upstream and downstream municipality of Trento). Significant correlation between the standard and Fpg - modified comet assay indicated that oxidative stress could be a major contributor to observed DNA damage in collected specimens.
dc.relationinfo:eu-repo/grantAgreement/EC/FP7/603629/EU//
dc.relationThis study represents a part of activities within the Projects funded by the Ministry of Education, Science and Technological Development of the Republic of Serbia and bilateral project Serbia and Slovenia BI-RS/14-15-013
dc.rightsopenAccess
dc.sourceScience of The Total Environment
dc.subjectTrout
dc.subjectAdige River
dc.subjectEcogenotoxicology
dc.subjectComet assay
dc.subjectMicronucleus
dc.titleEvaluation of genotoxic potential throughout the upper and middle stretches of Adige river basin
dc.typearticle
dc.rights.licenseBY-NC-ND
dcterms.abstractСимоновић, Предраг; Мајоне, Бруно; Диамантини, Елена; Пауновић, Момир; Вуковић-Гачић, Бранка; Беллин, Aлберто; Крачун-Коларевић, Маргарета; Гачић, Зоран; Петровић, Мира; Стелла, Елиса; Коларевић, Стоимир; Јовановић, Јована; Илић, Марија; Марковић, Вања; Симић, Владица;
dc.rights.holder© 2016 The Authors
dc.citation.volume571
dc.description.otherScience of The Total Environment (2016), 571: 1383-1391
dc.identifier.doi10.1016/j.scitotenv.2016.07.099
dc.identifier.pmid27450952
dc.identifier.scopus2-s2.0-84979519348
dc.identifier.wos000383930400138
dc.citation.apaKračun-Kolarević, M., Kolarević, S., Jovanović, J., Marković, V., Ilić, M., Simonović, P., Simić, V., et al. (2016). Evaluation of genotoxic potential throughout the upper and middle stretches of Adige river basin. Science of The Total Environment, 571, 1383–1391.
dc.citation.vancouverKračun-Kolarević M, Kolarević S, Jovanović J, Marković V, Ilić M, Simonović P, Simić V, Gačić Z, Diamantini E, Stella E, Petrović M, Majone B, Bellin A, Paunović M, Vuković-Gačić B. Evaluation of genotoxic potential throughout the upper and middle stretches of Adige river basin. Sci Total Environ. 2016;571:1383–91.
dc.citation.spage1383
dc.citation.epage1391
dc.type.versionpublishedVersionen
dc.identifier.fulltexthttp://ibiss-r.rcub.bg.ac.rs//bitstream/id/3474/SciTotalEnviron_2016_571_1383-1391.pdf
dc.citation.rankaM21


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record