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dc.creatorMilošević, Zorica C.
dc.creatorNadrljanski, Mirjan M.
dc.creatorMilovanović, Zorka M.
dc.creatorGušić, Nina Z.
dc.creatorVučićević, Slavko S.
dc.creatorRadulović, Olga
dc.date.accessioned2017-11-23T11:29:25Z
dc.date.available2017-11-23T11:29:25Z
dc.date.issued2017
dc.identifier.issn1318-2099
dc.identifier.urihttp://www.degruyter.com/view/j/raon.2017.51.issue-2/raon-2017-0016/raon-2017-0016.xml
dc.identifier.urihttps://ibiss-r.rcub.bg.ac.rs/handle/123456789/2781
dc.description.abstractWe aimed to analyse the morphokinetic features of breast fibrocystic changes (nonproliferative lesions, proliferative lesions without atypia and proliferative lesions with atypia) presenting as a non-mass enhancement (NME)in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) examination. Forty-six patients with histologically proven fibrocystic changes (FCCs) were retrospectively reviewed, according to Breast Imaging Reporting and Data System (BI-RADS) lexicon. Prior to DCE-MRI examination, a unilateral breast lesion suspicious of malignancy was detected clinically, on mammography or breast ultrasonography. The predominant features of FCCs presenting as NME in DCE-MRI examination were: unilateral regional or diffuse distribution (in 35 patients or 76.1%), heterogeneous or clumped internal pattern of enhancement (in 36 patients or 78.3%), plateau time-intensity curve (in 25 patients or 54.3%), moderate or fast wash-in (in 31 patients or 67.4%).Nonproliferative lesions were found in 11 patients (24%), proliferative lesions without atypia in 29 patients (63%) and lesions with atypia in six patients (13%), without statistically significant difference of morphokinetic features, except of the association of clustered microcysts with proliferative dysplasia without atypia. FCCs presenting as NME in DCE-MRI examination have several morphokinetic features suspicious of malignancy, therefore requiring biopsy (BI-RADS 4). Nonproliferative lesions, proliferative lesions without atypia and proliferative lesions with atypia predominantly share the same predefined DCE-MRI morphokinetic features.
dc.rightsopenAccess
dc.sourceRadiology and Oncology
dc.subjectBbreast
dc.subjectMagnetic resonance imaging
dc.subjectFibrocystic changes
dc.titleBreast dynamic contrast enhanced MRI: fibrocystic changes presenting as a non-mass enhancement mimicking malignancy
dc.typearticle
dc.rights.licenseBY-NC-ND
dcterms.abstractГушић, Нина З.; Радуловић, Олга С.; Миловановић, Зорка М.; Надрљански, Мирјан М.; Вучићевић, Славко С.; Милошевић, Зорица Ц.;
dc.rights.holder© 2017 Radiol Oncol.
dc.citation.issue2
dc.citation.volume51
dc.identifier.doi10.1515/raon-2017-0016
dc.identifier.pmid28740447
dc.identifier.scopus2-s2.0-85020436866
dc.identifier.wos000401697000002
dc.citation.apaMilosevic, Z. C., Nadrljanski, M. M., Milovanovic, Z. M., Gusic, N. Z., Vucicevic, S. S., & Radulovic, O. S. (2017). Breast dynamic contrast enhanced MRI: fibrocystic changes presenting as a non-mass enhancement mimicking malignancy. Radiology and Oncology, 51(2), 130–136.
dc.citation.vancouverMilosevic ZC, Nadrljanski MM, Milovanovic ZM, Gusic NZ, Vucicevic SS, Radulovic OS. Breast dynamic contrast enhanced MRI: fibrocystic changes presenting as a non-mass enhancement mimicking malignancy. Radiol Oncol. 2017;51(2):130–6.
dc.citation.spage130
dc.citation.epage136
dc.type.versionpublishedVersionen
dc.identifier.fulltexthttp://ibiss-r.rcub.bg.ac.rs/bitstream/id/3362/bitstream_3362.pdf
dc.citation.rankM22


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