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dc.creatorAvdović, Edina H.
dc.creatorStojković, Danijela L.J.
dc.creatorJevtić, Verica V.
dc.creatorKosić, Milica
dc.creatorRistić, Biljana
dc.creatorHarhaji Trajković, Ljubica
dc.creatorVukić, Milena
dc.creatorVuković, Nenad
dc.creatorMarković, Zoran S.
dc.creatorPotočňák, Ivan
dc.creatorTrifunović, Srećko R.
dc.date.accessioned2017-11-23T11:28:44Z
dc.date.available2900-01-01
dc.date.issued2017
dc.identifier.issn0020-1693
dc.identifier.urihttp://linkinghub.elsevier.com/retrieve/pii/S0020169317301597
dc.identifier.urihttps://ibiss-r.rcub.bg.ac.rs/handle/123456789/2792
dc.description.abstractThe new coumarine derivative, 3-(1-(3-hydroxypropylamino)ethylidene)chroman-2,4-dione, and corresponding palladium(II) complex have been synthesized and characterized by microanalysis, infrared, 1H and 13C NMR spectroscopy. The structure of the ligand, solved using a monocrystal X-ray structural analysis, consists of two crystallographic different pseudocentrosymmetrically related molecules of 3-(1-(3-hydroxypropylamino)ethylidene)chroman-2,4-dione, while the structure of the square-planar palladium(II) complex was proposed on the basis of DFT calculations. The palladium(II) complex decreased viability of U251 human glioma and B16 mouse melanoma cells in a dose and time dependent manner, while its ligand exhibited only moderate cytotoxicity.
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172016/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/41010/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172021/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/41025/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173053/RS//
dc.relationBilateral project between Republic of Serbia and Slovak Republic No. SK-SRB-2013-0004
dc.relationProject VEGA No. 1/0598/14
dc.rightsrestrictedAccess
dc.sourceInorganica Chimica Acta
dc.subjectCoumarine-derived ligand
dc.subjectPalladium(II) complex
dc.subjectCytotoxicity
dc.subjectCrystal structure
dc.subjectApoptosis
dc.subjectOxidative stress
dc.titleSynthesis, characterization and cytotoxicity of a new palladium(II) complex with a coumarin-derived ligand 3-(1-(3-hydroxypropylamino)ethylidene)chroman-2,4-dione. Crystal structure of the 3-(1-(3-hydroxypropylamino)ethylidene)-chroman-2,4-dione
dc.typearticle
dc.rights.licenseARR
dcterms.abstractХархаји Трајковић, Љубица; Aвдовић, Едина Х.; Стојковић, Данијела Л.Ј.; Трифуновић, Срећко Р.; Поточňáк, Иван; Марковић, Зоран С.; Вукић, Милена; Вуковић, Ненад; Косић, Милица; Ристић, Биљана; Јевтић, Верица В.;
dc.rights.holder© 2017 Elsevier B.V.
dc.citation.volume466
dc.description.otherInorganica Chimica Acta (2017), 466: 188-196
dc.identifier.doi10.1016/j.ica.2017.06.015
dc.identifier.scopus2-s2.0-85020718781
dc.identifier.wos000410683500024
dc.citation.apaAvdović, E. H., Stojković, D. L. J., Jevtić, V. V., Kosić, M., Ristić, B., Harhaji-Trajković, L., Vukić, M., et al. (2017). Synthesis, characterization and cytotoxicity of a new palladium(II) complex with a coumarin-derived ligand 3-(1-(3-hydroxypropylamino)ethylidene)chroman-2,4-dione. Crystal structure of the 3-(1-(3-hydroxypropylamino)ethylidene)-chroman-2,4-dione. Inorganica Chimica Acta, 466, 188–196.
dc.citation.vancouverAvdović EH, Stojković DLJ, Jevtić V V., Kosić M, Ristić B, Harhaji-Trajković L, Vukić M, Vuković N, Marković ZS, Potočňák I, Trifunović SR. Synthesis, characterization and cytotoxicity of a new palladium(II) complex with a coumarin-derived ligand 3-(1-(3-hydroxypropylamino)ethylidene)chroman-2,4-dione. Crystal structure of the 3-(1-(3-hydroxypropylamino)ethylidene)-chroman-2,4-dione. Inorganica Chim Acta. 2017;466:188–96.
dc.citation.spage188
dc.citation.epage196
dc.type.versionpublishedVersionen
dc.citation.rankM22


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