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dc.creatorProkić, Marko
dc.creatorGavrić, Jelena
dc.creatorPetrović, Tamara
dc.creatorDespotović, Svetlana
dc.creatorGavrilović, Branka
dc.creatorRadovanović, Tijana
dc.creatorKrizmanić, Imre
dc.creatorPavlović, Slađan
dc.date2020-05-10
dc.date.accessioned2019-05-14T11:32:00Z
dc.date.available2020-05-10
dc.date.issued2019
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S109564331930090X?via%3Dihub
dc.identifier.urihttps://ibiss-r.rcub.bg.ac.rs/handle/123456789/3338
dc.description.abstractDuring life, anuran individuals undergo drastic changes in the course of transition from aquatic to terrestrial habitat, when they are faced with metabolically demanding processes (growth, responses to developmental pressures), which result in increased production of reactive oxygen species (ROS), signaling molecules involved in development that can induce oxidative damage and stress. This situation can be further complicated by environmental influences. The aim of this study was to investigate oxidative stress parameters in naturally developing Pelophylax esculentus complex frogs during four developmental periods: premetamorphosis, prometamorphosis, metamorphic climax and juvenile stage, in order to examine changes in the response of the antioxidative system (AOS) and oxidative damage during the transition from aquatic to terrestrial life. Results show that ontogenetic shifts in anurans are accompanied by different levels of damage and AOS responses, which vary from the increased first-line enzymatic activities during the early period of development (premetamorphosis), through increased changes in the non-enzymatic complement during the metamorphic climax, to changes in both the enzymatic and non-enzymatic components observed in juvenile individuals. Premetamorphic individuals and individuals in metamorphosis displayed higher levels of lipid peroxidation, indicating that direct exposure to the environment for the first time and the modulation of organs are the most susceptible stages for oxidative damage. On the other hand, lower oxidative damage in juveniles points to the ability of their AOS to efficiently respond to challenges of the terrestrial environment. This study highlights the importance of ROS and the AOS of anurans in response to different developmental and/or environmental pressures that individuals face.
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173041/RS//
dc.rightsembargoedAccess
dc.sourceComparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology
dc.subjectAnurans
dc.subjectAntioxidative system
dc.subjectDevelopment
dc.subjectOxidative stress
dc.subjectTadpoles
dc.subjectJuvenile
dc.titleOxidative stress in Pelophylax esculentus complex frogs in the wild during transition from aquatic to terrestrial life
dc.typearticleen
dc.rights.licenseBY-NC-ND
dcterms.abstractПавловић, Слађан; Петровић, Тамара; Деспотовић, Светлана; Гавриловић, Бранка; Радовановић, Тијана; Кризманић, Имре; Прокић, Марко; Гаврић, Јелена;
dc.rights.holder© 2019 Elsevier Inc.
dc.identifier.doi10.1016/J.CBPA.2019.05.004
dc.identifier.scopus2-s2.0-85065559669
dc.identifier.wos000472813300011
dc.citation.apaProkić, M. D., Gavrić, J. P., Petrović, T. G., Despotović, S. G., Gavrilović, B. R., Radovanović, T. B., … Pavlović, S. Z. (2019). Oxidative stress in Pelophylax esculentus complex frogs in the wild during transition from aquatic to terrestrial life. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, DOI:10.1016/J.CBPA.2019.05.004.
dc.citation.vancouverProkić MD, Gavrić JP, Petrović TG, Despotović SG, Gavrilović BR, Radovanović TB, Krizmanić II, Pavlović SZ. Oxidative stress in Pelophylax esculentus complex frogs in the wild during transition from aquatic to terrestrial life. Comp Biochem Physiol Part A Mol Integr Physiol. 2019;DOI:10.1016/J.CBPA.2019.05.004.
dc.type.versionacceptedVersion
dc.identifier.fulltexthttp://ibiss-r.rcub.bg.ac.rs/bitstream/id/4990/CompBiochemPhysiolPartAMolIntegrPhysiol_2019.pdf
dc.citation.rankM21


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