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dc.creatorMartać, Ljiljana
dc.creatorPodgorac, Jelena
dc.creatorPetković, Branka
dc.creatorSekulić, Slobodan
dc.creatorCapo, Ivan
dc.date.accessioned2020-07-16T08:58:35Z
dc.date.available2020-07-16T08:58:35Z
dc.date.issued2015
dc.identifier.issn2413-8878
dc.identifier.urihttp://arpgweb.com/?ic=journal&journal=16&info=aims
dc.identifier.urihttps://ibiss-r.rcub.bg.ac.rs/handle/123456789/3777
dc.description.abstractThis paper presents an overview of rat animal model of Alzheimer’s disease. Model is based on the toxicity, oxidative stress and neurodegeneration. The model is obtained by treatment of rats with intraperitoneal aluminum. Electrocortical group neuron activity describes changes in neurotransmission caused by different factors. Such changes could be qualitatively described by spectral and fractal analysis of electrocortical activity as a variation of the relative spectral power. Both animals and patients with Alzheimers demention have increased relative spectral power in delta range. By fractal analysis we described changes in electrocortical activity of aluminum intoxication animals compare to physiological control. We used change in delta range to calculate fractal dimension. Also we used fractal dimension to compare treated animals with control ones to quantitatively describe the degree of pathophysiological state. All changes are correlated with an increase in the relative spectral power in the delta range and can be quantitatively described by fractal dimension. Results are presented as the effect and can also be applied to the human model of neurotoxicity and neurodegeneration like Alzheimer’s dementia. The model itself may be used for diagnostic and prognostic purposes since it describes the parameters underlying Alzheimer’s disease. However in definition of disease should be consider a state of dementia and menthal activity.sr
dc.language.isoensr
dc.publisherAcademic Research Publishing Groupsr
dc.rightsopenAccesssr
dc.sourceJournal of Biotechnology Researchsr
dc.subjectToxicitysr
dc.subjectIonian disbalanssr
dc.subjectOxidative stresssr
dc.subjectFractal analysissr
dc.subjectSpectral powersr
dc.titleSpectral and Fractal Analysis of ECoG in Animal Model of Aluminium Intoxicationsr
dc.typearticlesr
dc.rights.licenseBYsr
dcterms.abstractЦапо, Иван; Подгорац, Јелена; Мартаћ, Љиљана; Секулић, Слободан; Петковић, Бранка;
dc.rights.holder© 2015 Academic Research Publishing Groupsr
dc.citation.issue5
dc.citation.volume1
dc.citation.spage21
dc.citation.epage25
dc.type.versionpublishedVersionsr
dc.identifier.fulltexthttp://ibiss-r.rcub.bg.ac.rs/bitstream/id/6487/bitstream_6487.pdf


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