PCR amplifikacija sedam nuklearnih gena Beogradske mumije
PCR amplification of seven single copy nuclear genes from the Belgrade mummy
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Here we report a DNA analysis of a human mummy dated approximately 2300 years BC. We extracted the DNA and used it for further PCR amplification of the following genes: c-fms proto-oncogene for CSF-1 receptor gene (CSF1PO); coagulation factor XIII a subunit gene (F13A01); c-fes/fps proto-oncogene (FESFPS); tyrosine hydroxylase gene (TH01); thyroid peroxidase gene (TPOX), von Willebrand factor gene (vWA) and Y chromosome specific sequence. The alleles from Belgrade mummy do not differ from the most frequent alleles of all present human populations. The exception is FESFPS gene. Belgrade mummy is homozygous for this locus which contains alleles with 7 motif repeats while such allele is found in less than 0.38% of living humans.